I'm hesitant to describe my mental state... it hasn't really changed. I'm miserable. I've been miserable since I was a child. I don't know if it's what clinicians would call depression. Can you be depressed for, essentially, your whole life? I'm experiencing some personal and financial set backs right now, and I'm wondering... I don't feel different. When I'm doing the 'normal' things--working, socializing with relatives, 'hobbies'--I'm still miserable. When I'm unemployed and isolated I feel miserable. I feel stuck. Trust me when I say I don't feel human. I don't relate to others. They appear just like that: others. I have no interest in anything.
I'm chronically stressed for no apparent reason. I feel like people are going to shout at me suddenly, hit me, or otherwise assault me. I feel completely stuck. I'm on antidepressants. I'm on some other medications too. None of it helps. I could be taking placebos. My body really does not respond to them, and the psychiatric appointments are so infrequent due to packed schedules, that it's overwhelmingly disappointing. I wait months to say "they don't work" only to be told "we'll up the dosage". They don't work. I don't feel any different.
Psychologists are a complete waste of time. They nod their head and espouse common sense/platitudes. I always feel worse after seeing one, because it just hammers home the idea that no one can help how I feel. I get it. Only I can do that, but I feel my brain is damaged and it's not functional--I've experienced head traumas, chronic neglect (from years 0-19), and electrocution. Because I wasn't sent to school I don't have an authoritative record of childhood behavioral issues. I relate very much to ADHD symptoms, but everyone is reluctant to allow me to try those medications that might help that disorder. I feel like, as much as I try to explain, they just don't understand my issues. I'm borderline nonfunctional, but because I present groomed, wearing an ironed shirt and slacks, I feel like they don't believe me.
I want a break emotionally. I want to feel something other than an overwhelming sense of misery, disinterest, and hopelessness.
I like your questions blues. I feel we have come from similar backgrounds. I've just passed the 20s, and my life has been not worth it. I'd be relieved to die any day (or to have died at any point prior). My parents were abusive, my extended family were dysfunctional, and my childhood was isolation incarnate. I think this question's heading is life, although it skirts around that. Suicide is painful. If anyone manages to commit then that's the right time for them. It really is not something one can just "choose". It's not a choice.
I don't think material conditions play much into this decision, though when articulated it may appear they do. "I don't have friends," "I don't have a car", "I don't have a non-degrading job", "I don't have a house", etc. It's a feeling. One could have everything they thought they craved and still feel miserable and despondent. One could have nothing and be in high spirits. I don't think anyone knows how to control emotions enough that they're able to guide someone to a social 'norm'. I'd suggest engaging with doctors though, and that ranges through to the general practitioner to the specialized psychiatrist, and all those professions in between.
History abounds with morose writings. It's not a new question, and I don't think it'll ever have a definitive answer. Just keep trying different things, and keep talking to others as much as you can, because whilst an individual might not have a definitive answer you usually can find something with enough data.