food
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Ingredients of the week: Mushrooms,Cranberries, Brassica, Beetroot, Potatoes, Cabbage, Carrots, Nutritional Yeast, Miso, Buckwheat
Cuisine of the month:
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It's safer to boil them in lemon juice and and water and then drink the juice. There's two compounds, both are delirients, but one is toxic. Boiling them in acid reduces the quantity of the toxic one (and in fact turns it into the non toxic one).
Not a deliriant, it's a weird gabaergic like Ambien
https://m.psychonautwiki.org/wiki/Amanita_muscaria Muscimol has an atypical mechanism of action. Unlike classical psychedelics (which are 5-HT2A agonists) and classical dissociatives (which are NMDA receptor antagonists), muscimol is a potent GABAA agonist, meaning it activates the receptor for GABA, the brain's principle inhibitory neurotransmitter. As an agonist, muscimol binds to the same site on the GABAA receptor as GABA itself. This is unlike benzodiazepines and barbiturates, which bind to different allosteric sites on the GABAA receptor.
Muscimol has also been shown to be a partial agonist at the GABAA-ρ receptor, which may contribute to its psychoactive effects. Activation of α1 subunit GABA receptors is responsible for the hallucinogenic effects of certain GABAergic compounds such as z-drugs, including zolpidem, and muscimol.[7]
The effects of isolated muscimol begin approximately one hour after consumption, peaking at 3 hours and lasting a total of 10-24 hours.[8]
Ibotenic acid has been shown to be a potent NMDA agonist as well as a powerful agonist at the group I and group II metabotropic glutamate receptors. Due to in vivo decarboxylation, ibotenic acid is metabolized to muscimol and thus has many similar pharmacological characteristics
Also if you were ever a heavy ambien user, Amanitas don't do shit. Even the tolerance is related.