in terms of prevention? Comodo, as far as commonly used solutions go, you need to know how to configure it though you also need to know how to handle the alerts it gives you and understand that it won't ever give you an alert when everything is fine, that's the catch. A lot of people have fucked up their entire computer when using comodo because they didn't configure it correctly or blocked/sandboxed the wrong thing.
in terms of detection? Kaspersky, Bitdefender, Sophos, microsoft defender with configure defender on MAX, Avast/AVG
Avast and AVG are owned by the same company
Avira is also pretty good in terms of detection, but the setup file will never go away even after you uninstall it.
I'm not going to reveal what my security setup is, there's a certain someone that's probably going to end up on Lemmy who I've encountered on many of their sock puppet accounts. That person is definitely stalking my posts and comments on reddit after some of the stuff I've said to them.