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FDA says cancer treatment CAR-T therapy may increase risk of cancer (www.nbcnews.com)

submitted 10 months ago by [email protected] to c/[email protected]

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The agency is requiring drugmakers to add a warning label to its CAR-T therapy products, but it noted that the benefits of the treatment still outweigh the potential risks.

The Food and Drug Administration this week told several drugmakers to add a boxed warning — the agency’s strongest safety label — to the prescribing information for a type of cancer treatment called CAR-T therapy, saying the treatment itself may increase a person’s risk of cancer.

Carly Kempler, a spokesperson for the FDA, said that, despite the warning, "the overall benefits of these products continue to outweigh their potential risks."

The agency’s decision to update the labels was based on reports of rare blood cancers in patients who had previously gotten CAR-T therapy, Kempler said. As of Monday, the agency had received 25 reports of the blood cancers in CAR-T patients, she said.

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[–] [email protected] 5 points 10 months ago (1 children)

Well, radiation is known to cause cancer and we use that to fight cancer also. So long as it's more likely to reduce the problem than make it worse, then yeah, have a warning, but it's not out of the ordinary.

[–] [email protected] 5 points 10 months ago

All chemotherapy agents are also well known to cause cancer, so much that you have to have special training as a nurse to handle them, special hazardous disposal, and lifelong monitoring for other cancers after completing treatment. So I feel like this shouldn't be that surprising to anyone.