137
New Alzheimer's Nasal Spray Clears Toxic Tangles in Human Neurons And Mice
(www.sciencealert.com)
just science related topics. please contribute
note: clickbait sources/headlines aren't liked generally. I've posted crap sources and later deleted or edit to improve after complaints. whoops, sry
Rule 1) Be kind.
lemmy.world rules: https://mastodon.world/about
I don't screen everything, lrn2scroll
I'm convinced that the Alzheimer's field is one of the areas of research that will be looked back upon with disillusionment.
Tau tangles and beta plaques have been fiercely and dogmatically pursued as causes and therapeutic targets of Alzheimer's disease. However, it is becoming increasingly clear that these aggregations are likely a consequence of the disease that does not necessarily present an avenue for therapy. I.e. the harmful part of the disease probably acts upstream of or in parallel to the accumulation of the tau and beta aggregations
All because Sylvain Lesné and team published a fraudulent research paper in 2006. The field has possibly lost a decade of time and money.
TIL. Damn.
Reminds me of the how early the covid policies were based on age-old misconceptions about aerosols.
How do you explain that amyloid-targetting therapies are seeing some success, even if limited?