I've been playing Diablo IV too. First non Steam game I tried on the Deck, and how well it works blows my mind. Used decky to put in custom artwork too so it fits right in with the rest of my games.
I've been playing around with a set up where I use the right touchpad to enter mouse mode and click to attack for times I need to aim. But, rest of the inputs are gamepad. What I'd like to do is have it so when I touch the right pad it modeshifts the right trigger into a left mouse click too. Could do same with action layers, but I'm hoping for a more straight forward and less problematic modeshift option.
I think setting up gyro in that case would work better than the touch screen. That's how I played through Maro Galaxy back in the day using the Steam Controller and having gyro only activate when I touched the right pad so it wasn't always going crazy.