WINE does not officially support NTFS as it is not optimal on Linux, even if you can technically read/write to it. So save yourself the headache and simply install your games on something like btrfs, xfs, or ext4 instead for playing games on Linux.
https://gitlab.winehq.org/wine/wine/-/wikis/FAQ#does-wine-run-on-all-unix-filesystems
Proton use wine and bundles dxvk and other tools, so it also has the same issue.
Windows doesn’t support any of the mentioned file systems out of the box, but there is a btrfs driver available.
There also is the more inconvenient option of creating symlinks for the games on a supported file system: Guide