this post was submitted on 10 Sep 2023
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3,3′-Diindolylmethane (DIM) decreased the Streptococcus mutans biofilm, a leading contributor to plaque and cavities, by 90%.

A significant portion of the global population experiences persistent issues with dental plaque and cavities or will face them at some time. While toothpaste, mouthwash, and routine dental visits help in prevention, there’s always room for improvement.

Researchers from Ben-Gurion University of the Negev, in collaboration with teams from Sichuan University and the National University of Singapore, have identified that 3,3′-Diindolylmethane (DIM) – a naturally occurring molecule also referred to as bisindole – can reduce biofilms responsible for plaque and cavities by a remarkable 90%.

The molecule is also found to have anti-carcinogenic properties.

Their findings were recently published in the journal Antibiotics.

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[–] [email protected] 83 points 1 year ago (1 children)

Incredible. Given how expensive dental treatment is in a lot of places, this could be revolutionary for people who can't afford regular checkups and/or treatment plans. It's not going to be a replacement but it can certainly mitigate a lot of damage.

[–] [email protected] 33 points 1 year ago (2 children)

I mean if the research a few months ago in japan that detailed the ability to introduce a drug to allow teeth growth beyond the second pair has good results, things are getting places.

[–] [email protected] 18 points 1 year ago

From my understanding , it wasn't past the second pair, it was to reactivate deactivated teeth.

As in, they artificially induced a way to stop a tooth forming (which can occur naturally in humans), and then reactivated it. Useful for folks who suffer from agenesis in the first place.

[–] [email protected] 64 points 1 year ago (1 children)

Dentists hate this one complex molecule

[–] [email protected] 14 points 1 year ago (1 children)

Fuck'm. I'm pretty sure most of my "small cavities" over the years were nothing, especially in the 80s. Medieval butchery.

[–] [email protected] 20 points 1 year ago

As grandpa said "don't go to the dentist, they want you to keep your teeth as long as possible so they can keep billing you"

[–] [email protected] 53 points 1 year ago (1 children)

Well let's hope the mass adoption of this ingredient in everyone's toothpaste doesn't make the gray water kill all the birds or frogs or something. Ecosystems are weird. Diclofenac fucks all the vultures and I found out recently.

[–] [email protected] 8 points 1 year ago

The rub on cremes especially. How come everything we touch turns to hellscape.

[–] [email protected] 40 points 1 year ago (1 children)

Does it occur naturally in anything or would it be a toothpaste ingredient?

[–] [email protected] 56 points 1 year ago* (last edited 1 year ago) (5 children)
[–] [email protected] 24 points 1 year ago

For anyone wondering, all those are the same species.

Brassica oleracea.

[–] [email protected] 18 points 1 year ago

That must be why my teeth have never been a problem. Fuckin love broccoli

[–] [email protected] 7 points 1 year ago (1 children)

Of course... the group of veggies that taste like farts. 🤢

[–] [email protected] 7 points 1 year ago

Roast them with some oil, salt, and pepper and you won’t be saying that

[–] [email protected] 7 points 1 year ago

Yay cabbage!

[–] [email protected] 5 points 1 year ago (1 children)

DIM was found to be a mild cannabinoid agonist

Interesting...

[–] [email protected] 4 points 1 year ago

agonist

Weed does everything!

[–] [email protected] 27 points 1 year ago (3 children)

Conservatives are already furious about this. I mean, it's an obvious trick to install 5G tracking chips to allow the globalists to track everyone for the new world order where all men will be forced to pee sitting down in their mandatory pink bathrooms.

[–] [email protected] 31 points 1 year ago* (last edited 1 year ago) (3 children)

Americans reading anything: "How do I find a way to shove our idiotic polarized, tribal politics into this?".

Seriously. It's an article about dental health...

[–] [email protected] 3 points 1 year ago (1 children)

Our conservatives are the number one threat to humanity world-wide. You should care about this because it will eventually affect you directly.

[–] [email protected] -2 points 1 year ago* (last edited 1 year ago)

I repeat. It's an article about dental health. You can pretend your comment was anything other than you circlejerking the same tired bullshit without saying a single fucking thing, just to stroke your ego and feel like you're any better than the people you make fun of all you want. It doesn't change a thing. You repeating some hyperlative bullshit doesn't either. It just reveals who you are.

Very well aware of the threat of American idiots, mainly due to the fact that because people exactly like you on the other side of the spectrum keep shoving the same bullshit down everyone's throats everywhere they go, it spreads and now, thanks to exactly the same behavior you're so proud of here, we have idiots all over the world repeating the same idiocy down to a tee.

Just because people don't want your dick shoved down their throats 24/7 everywhere they go doesn't mean they don't care.

"Conservatives are like: "Herppp derppp I'm a conservative there's microchips in ma teef!" Hahaha! Right guys?!" isn't exactly the kind of eloquent and well thought argument you think it is. Behaviour like that contributes to the problem, it doesn't solve anything. You're a part of the problem. Be better.

[–] [email protected] 3 points 1 year ago

They're fucking everywhere. They're coming out of the fucking wall!!

[–] [email protected] 2 points 1 year ago (1 children)

They don't admit it but they love their culture wars and shit politics.

[–] [email protected] 10 points 1 year ago (2 children)

I always sit down to pee when possible. It's a nice little break in my busy day.

[–] [email protected] 7 points 1 year ago (2 children)

And who wants to turn the light on in the middle of the night.

[–] [email protected] 3 points 1 year ago (1 children)

Takes the fun out of aiming by sound, too.

[–] [email protected] 2 points 1 year ago

I currently hold the high score in Night Pisser.

Nothing affirms my masculinity quite like that reassuring tinkle after adjusting from the spitter-spatter of dry porcelain.

[–] [email protected] 3 points 1 year ago (1 children)

Get a night light for the bathroom. It won't blind you, and you don't have to fumble around in the dark while half asleep.

[–] [email protected] 1 points 1 year ago* (last edited 1 year ago)

Brilliant! I will subscribe for more tips!

[–] [email protected] 5 points 1 year ago

You take that practicality back to whatever commie hell hole spawned you, you heathen!

[–] [email protected] 5 points 1 year ago

It turns you into a gay frog even faster than fluoride!

[–] [email protected] 23 points 1 year ago (1 children)

Expect people claiming it makes them dumb

[–] [email protected] 5 points 1 year ago (2 children)
[–] [email protected] 4 points 1 year ago

#JustCavityThings

[–] [email protected] 2 points 1 year ago

#JustColgateThings

[–] [email protected] -3 points 1 year ago* (last edited 1 year ago) (5 children)

Alcohol-based mouth sanitizer will kill like 99.9% of bacteria in your mouth, the issue is that you won't keep it in your mouth 24 hours a day.

Is this new chemical supposed to be added to food, or maybe to sugar?

[–] [email protected] 59 points 1 year ago (1 children)

The point isn't that it kills bacteria, it's that it breaks down the biofilm.

The biofilm is basically habitat - it's a structure they can cling to and establish a foothold.

Mouths are never going to be a sterile environment even a minute after nuking with alcohol; populations will re-establish in no time.

The point here is to deny them a place to stay.

[–] [email protected] 10 points 1 year ago

That makes sense

[–] [email protected] 18 points 1 year ago

You really don't want to kill all the bacteria in your mouth.

[–] [email protected] 3 points 1 year ago* (last edited 1 year ago)

Those mouth washes don't get rid of plaque caused by the bacteria, though. Just the bacteria.

[–] [email protected] 1 points 1 year ago

Sounds like this molecule is already found in broccoli, kale, Brussels sprouts, and cabbage.