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AI that simulates protein evolution (the-decoder.com)

submitted 11 hours ago by [email protected] to c/[email protected]

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Unlike traditional language models that only learn from textual data, ESM3 learns from discrete tokens representing the sequence, three-dimensional structure, and biological function of proteins. The model views proteins as existing in an organized space where each protein is adjacent to every other protein that differs by a single mutation event.

They used it to "evolve" a novel protein that acts similarly to others found in nature, while being structurally unique.

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