Baldur’s Gate 3 is a story-rich, party-based RPG set in the universe of Dungeons & Dragons, where your choices shape a tale of fellowship and betrayal, survival and sacrifice, and the lure of absolute power. (Website)
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My least favorite fight in the game. On my last honor mode run, Isobel started her turn by triggering Attacks of Opportunity from both Marcus and one of the undead. The second one paralyzed her, of course. She's lucky I happened to have a cleric in that party that could Sanctuary right after, otherwise she would have been gone.
Have you tried not missing?
Skill issue
I want to see those detailed rolls.
Marcus' AC is only 17 so you had some horrible luck.
Only?! Isn't that high?
Not especially. For as early as you can encounter Marcus in act 2 it's pretty high though. I usually save his fight for right before I head to grab Dame Aylin and have gotten a bit more powered up.
After more thought on the matter though I bet OP has karmic dice on. That option being on can make those crazy long bad and good luck streaks happen.
I turned karmic dice off all the way back in the mindflayer ship when that lvl.5 demon thing was when weaving my lvl.1 party and I thought the game was broke
That's XCOM, baby.
Oh, wait...
Really screws with you when you miss multiple 70+% rolls in a row
Have you tried using a bucket full of water?
I use a fine spray bottle for this fight instead. I mist where op missed.