Games

Tunic.

The one thing I think is worth “spoiling” just to save you some pain:

I also second Outer Wilds.

13 Sentinels: Aegis Rim.

Do not go in knowing anything.

The most I will tell you is that it's an adventure game with some minor tower defense elements. And that it is the best game I've ever played, and no game has ever topped it since.

The Legend of Zelda: Breath of the Wild

And probably Tears of the Kingdom too but I haven’t played it yet.

I'm disappointed that nobody's mentioned Pony Island yet.

Bioshock.

Warframe. Focus on the Main Quest. That is all.

The Zero Escape Series. I wish I could play it again without knowing anything.

Same with Professor Layton games (for the big plots).

Chants of Senaar - You interpret alien languages.

Inside. Made by the same company as Limbo, but Inside is much more "don't look up a single thing"

The Long Dark

Getting lost in the snowy wilderness I so much fun. I have many "oh shit" moments that kinda don't happen once you learn the maps and improve.

Inscryption

Dark souls

Will second Doki Doki Literature Club. Undertale should also be on this list I feel.

Factorio and Dyson Sphere Program. At least don't watch people like Nilaus and Dosh Doshington play the game until you've tried to make your own solutions first.

Dark Souls and Return of the Obra Dinn have already been mentioned, but I'll also recommend Universal Paperclips. These also happen to be my favorite 3 games.

Sauna2000 (it's not out yet, but there are some demos floating around).

Squirrel stapler

Cruelty Squad - depends on the kinda person you are. If you're super open-minded about game presentation then I'd tell you to go into it blind. If not, then I'll happily try to sell you on it. If it helps, the game looks the way that it does because of how fucking confident it is in itself; and that confidence is fully justified. Give it time, even if the first level doesn't hook you, give it time because in my experience it will eventually hook you and reel you in and leave you thinking it's one of the best games of all time.

Undertale

Hypnospace Outlaw

Jet Set Radio, Jet Set Radio Future, Bomb Rush Cyberfunk. Give the first two a try, and if you don't like either one, skip BRC; it's a spiritual successor to JSRF and if you didn't like JSRF then you probably won't like BRC.

Hylics. If you liked that and wanted more, Hylics 2. Hylics 2 actually does something throughout the game that I've only ever seen as a gimmick in other games. It's really cool and it'll probably catch you off-guard every time it does it.

Katamari Damacy. If you liked that, there's also We <3 Katamari.

Myst. The newest version has VR support. If you liked that, the recent Riven remaster also has VR support.

S C O R N (if you like Myst, give it a try. It feels very myst-like)

Hrot (boomer shooter, but if you like boomer shooters then you should give it a go).

If you're at a place in your life where you're trying to still find yourself: Night in the Woods. Especially if you're a furry. This game is really fucking good. It'll make you laugh. It'll make you cry. It'll make you miss home but also be glad you aren't there anymore. It'll make you question your place in life and who you are. Also, you can interact with things multiple times, make sure you don't miss out on dialogue, you'll regret it.

STALKER: Shadow of Chernobyl - This is hard to go into blind because it's buggy as fuck and most people recommend some form of community patch even for your first playthrough. That said, play it on the highest difficulty. It's unironically more fun once you get used to it. If it's too hard though, don't be fooled into thinking that dropping the difficulty will make it easier, the hardest difficulty is special (you can only take a few hits, but the same is true for most enemies), and dropping it down will result in enemy difficulty scaling becoming more traditional (buffing health and damage).

Portal (and Portal 2).

Bugsnax.

If I can throw in a movie too:

Willy's Wonderland. It's a Nicolas Cage movie and that's all I'll tell you. DO NOT LOOK UP THE TRAILER. I wouldn't have watched it if I hadn't seen the trailer, but the trailer also has huge spoilers. I'm not a huge movie person and I had to watch it after seeing the trailer, but again the trailer has spoilers. It is on my top-10 movies list now.

Soma

Prey 2017 can be incredible blind and Dredge might be worse if you’ve had the ending spoiled

Detroit: Become Human

Gris

Stray

I'm gonna go with Skyrim, the more unoptimized and aimless your playthrough is, the more fun you'll have.

Most of the really good games have been posted already, so here are three that you should play regardless if you’ve never heard of them before:

1. Frog Fractions
2. Duty Calls: The Calm Before the Storm
3. GAME OF THE YEAR 420 BLAZE IT

Check them all out because they’re short and free

Silent Hill 2 and SOMA

Helltaker

Free, short, puzzles, cute, and banger ost

I believe Cyberpunk 2077 is a fantastic experience going in blind.

Gods Will Be Watching and The Red Strings Club

Spec Ops: The Line